Chronic stress could be the prevailing condition of our time. In the short term, our jaws or stomachs may clench; in the long term, stress can lead to metabolic disease and speed up diseases of aging, as well as leading to more serious psychological disorders. The physical manifestations of stress originate in the brain, and they move along a so-called ‘stress axis’ that ends in the adrenal glands. These glands then produce the hormone cortisol. When the stress axis is continually activated, changes occur in the cells and organs along the way, and the continual production of cortisol then substantially contribute the symptoms of chronic stress.