Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies. The protein indirectly switches on an important intracellular signaling pathway active while the embryo develops, but which shuts down in healthy cells of adults. Far Eastern Federal University (FEFU), the University of Geneva, and the Institute of Protein Research (Russia) scientists describe the problem in Scientific Reports.