Wuhan City in China was the first place to report COVID-19 in the world and—between December 2019 and May 2020—caused nearly two-thirds of all COVID-19 cases in China. Now, researchers reporting in PLOS Neglected Tropical Diseases have tested more than 60,000 healthy individuals in China for SARS-CoV-2 antibodies and concluded that thousands of Wuhan residents were infected with asymptomatic cases of COVID-19 after the infection was believed to be under control in China.