Urine bicarbonate test offers new, safe quantification of CFTR function in cystic fibrosis patients

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Urine bicarbonate test offers new, safe quantification of CFTR function in cystic fibrosis patients

A study of 50 adult patients with cystic fibrosis (CF) has found that challenged urine bicarbonate excretion may offer a new, simple, and safe quantification of cystic fibrosis transmembrane conductance regulator (CFTR) function and the extent of its pharmacologic improvement. The study is published in Annals of Internal Medicine.

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