Downregulation of senescence-associated secretory phenotype by knockdown of SFRP4 contributes to skin aging prevention
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31 October 2022Downregulation of senescence-associated secretory phenotype by knockdown of SFRP4 contributes to skin aging prevention
There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging via an inflammatory, histolytic, and senescence-associated secretory phenotype (SASP).
