Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

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Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

A recent study published in Oncogene and led by Dr. Sun Yu’s group at Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences revealed the roles and functional mechanisms of senescence-associated secretory factor epiregulin (EREG) in treatment-damaged tumor microenvironments, providing a new therapeutic target and noninvasive biomarker for treatment of human malignancies including prostate cancer.

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