Huntington’s disease is a rare hereditary neurodegenerative pathology which usually manifests itself between the ages of 30 and 50. It is characterized by the emergence of motor, cognitive and psychiatric symptoms that alter the patient’s lives. Historically, motor and cognitive manifestations of the disease had been associated with the dysfunction of corticobasal circuits. However, it is now known that neurodegeneration gradually spreads to other structures of the brain such as the hippocampus, an important region for learning, memory and spatial orientation.