Scientists uncover role of Alzheimer’s-linked APOE gene in glaucoma protection and identify promising treatment
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16 August 2022Scientists uncover role of Alzheimer’s-linked APOE gene in glaucoma protection and identify promising treatment
New research led by scientists at Mass Eye and Ear and Brigham and Women’s Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer’s disease, APOE4, plays in protecting against glaucoma. In the new study, published August 16 in Immunity, the researchers also used a pharmacologic treatment to successfully prevent the destruction of neurons in the eyes of mice with glaucoma by targeting the APOE signaling pathway.
