Researchers at the University of Colorado Anschutz Medical Campus have investigated how antiviral proteins called interferons interact with SARS-CoV-2, the cause of COVID-19. The study, published in Proceedings of the National Academy of Sciences, focuses on how the innate arm of the immune system defends against this coronavirus. The work resulted from a collaborative effort by multiple scientists, including the laboratories of Mario Santiago, Ph.D., associate professor of medicine and Eric Poeschla, MD, professor of medicine, both at the University of Colorado School of Medicine.