Anticholinergics, a class of drugs frequently prescribed for depression, urinary incontinence and many other conditions common in older adults, affect the brain by blocking acetylcholine, a nervous system neurotransmitter which influences memory, alertness and planning skills. A new study from Regenstrief Institute, Purdue University College of Pharmacy and Indiana University School of Medicine researchers has found that using pharmacists as deprescribing care coordinators decreased prescription of anticholinergics by 73 percent and reduced cumulative use of these drugs by as much as 70 percent.