Tumor cells from some childhood leukemia block the formation of new neurons

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Tumor cells from some childhood leukemia block the formation of new neurons

Some of the relapses in patients with childhood acute lymphoblastic leukemia are due to the fact that the leukemia cells manage to survive treatment by hiding in areas of the Central Nervous System. Research led by Universidad Complutense de Madrid using an animal model shows the presence of leukemia cells in a previously unknown location: the subventricular neurogenic niche. The tumor cells that colonize this zone of the brain are capable of preventing the differentiation of new neurons

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