The Advisory Committee on Immunization Practices (ACIP) has released its 2022 Recommended Adult Immunization Schedule that includes changes to the zoster, pneumococcal, and hepatitis B vaccines. COVID-19 vaccinations are now included in the notes section of the schedule and can be co-administered with other vaccines. The authors say this year’s schedule is particularly important because many adults have fallen behind on routine vaccinations due to the COVID-19 pandemic. The complete schedule, including changes in the vaccine notes section, is being simultaneously published in Annals of Internal Medicine and in the Center for Disease Control and Prevention’s (CDC) Morbidity and Mortality Weekly Report (MMWR).