The American Academy of Neurology (AAN) has issued a guideline providing recommendations for treating movement symptoms, called motor symptoms, in people with early Parkinson’s disease. The guideline is published in the November 15, 2021, online issue of Neurology, the medical journal of the AAN, and is endorsed by the Parkinson’s Foundation. This guideline updates recommendations on dopaminergic medications that were published in the 2002 AAN guideline on the initiation of treatment for Parkinson’s disease.