Mathematical model reveals possible role of drug-eluting stents in artery re-closure

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Mathematical model reveals possible role of drug-eluting stents in artery re-closure

For patients with symptomatic coronary artery disease, the best course of action often involves implanting a drug-eluting stent into the artery where a plaque buildup is blocking blood flow to the heart. The metallic stent props the artery open while releasing a drug that helps to suppress restenosis—the re-closure of the artery due to excess tissue growth around the stent. However, the body’s response to tissue inflammation and arterial injury around the stent’s edges can still sometimes cause restenosis.

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