Researchers from the Brain Research Institute, Niigata University, Japan may have unraveled a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damage that could lead to Parkinson’s disease (PD). This novel finding utilizing cellular and zebrafish models, demonstrates how the leakage of mitochondrial dsDNA into the cytosol environment of the cell can contribute to the impairment of brain tissue of patients with PD.