DNA methylation changes in neurons of bipolar disorder patients
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9 June 2021DNA methylation changes in neurons of bipolar disorder patients
A research collaboration based in Kumamoto University, Japan, has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD). The regions with altered DNA methylation status were significantly enriched in genomic regions which were reported to be genetically related to BD. These findings are expected to advance the understanding of the pathogenesis of BD and the development of therapeutic drugs targeting epigenetic conditions.
