Aryl hydrocarbon receptor suppresses immunity to oral cancer through immune checkpoint regulation
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4 May 2021Aryl hydrocarbon receptor suppresses immunity to oral cancer through immune checkpoint regulation
A new Boston University School of Public Health (BUSPH) study has identified for the first time how the aryl hydrocarbon receptor (AhR), an environmental chemical receptor, drives immunosuppression in oral squamous cell carcinoma (OSCC)—and that its removal from malignant cells can result in tumor rejection.
