Metabolite fumarate can reveal cell damage: New method to generate fumarate for MRI

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Metabolite fumarate can reveal cell damage: New method to generate fumarate for MRI

A promising new concept published by an interdisciplinary research team in Proceedings of the National Academy of Sciences (PNAS) paves the way for major advances in the field of magnetic resonance imaging (MRI). Their new technique could significantly simplify hyperpolarized MRI, which developed around 20 years ago for observing metabolic processes in the body. The proposal involves the hyperpolarization of the metabolic product fumarate using parahydrogen and the subsequent purification of the metabolite.

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