Using samples of small cell lung tumors, a research team led by biologist Dr. Silvia von Karstedt has discovered two new ways to induce tumor cell death. One of two subsets of tumor cells can be targeted by activating ferroptosis: iron-dependent cell death caused by oxidative stress. In the second subtype, oxidative stress—and hence cell death—can also be induced in a different way. Both types of cell death must be triggered simultaneously by drugs to kill the majority of the tumor mass. The results of the study have been published in Nature Communications.