The lifting of masking requirements in school districts outside of Boston in February 2022 was associated with an additional 44.9 COVID-19 cases per 1,000 students and staff in the 15 weeks after the statewide masking policy was rescinded. This represented nearly 12,000 total COVID-19 cases or 30% of all cases in those school districts that unmasked during that time, according to a new study led by Harvard T.H. Chan School of Public Health, the Boston Public Health Commission, and Boston University School of Public Health.