The Presidential Symposium at the ongoing American Neurological Association 147th Annual Meeting has outlined major risks to neurological health from environmental exposures to pesticides, air pollution, synthetic materials, and more—now emerging as a major research area in neuroscience. The symposium, titled “Neurologic Dark Matter: Exploring the Exposome that Drives Neurological Disorders,” took place Sunday, October 23, at the Hyatt Regency Chicago.