Gestational exposure to flame retardant alters brain development in rats

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Gestational exposure to flame retardant alters brain development in rats

A new study from North Carolina State University shows that exposure in utero to the flame-retardant FireMaster 550 (FM 550), or to its individual brominated (BFR) or organophosphate ester (OPFR) components, resulted in altered brain development in newborn rats. The effects—most notably evidence of mitochondrial disruption and dysregulated choline and triglyceride levels in brain tissue—were greater in male offspring than in females.

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