Surprising discovery links Piezo1 and cholesterol during brain development

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Surprising discovery links Piezo1 and cholesterol during brain development

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.

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