Adults, especially older adults, may be in pain or depressed but not able to convey details of their symptoms and quality of life to their doctors for various reasons including cognitive impairment. A new study from Regenstrief Institute and Indiana University School of Medicine researchers investigates whether adult patients and their proxies—typically spouses, children or other family caregivers—agree on what they tell physicians about a patient’s symptoms and quality of life, information critical to clinical care.