Tenascin proteins inhibit regeneration of cell envelope

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Tenascin proteins inhibit regeneration of cell envelope

Researchers at Ruhr-Universität Bochum have been studying the role of the two proteins tenascin C and tenascin R in multiple sclerosis. In this disease, cells of the immune system destroy the myelin sheaths, i.e. the sheaths of the nerve cells. As the Bochum team showed in experiments with mice, the regeneration of the myelin sheaths is inhibited if the two tenascins are present. Dr. Juliane Bauch and Professor Andreas Faissner from the Cell Morphology and Molecular Neurobiology Department in Bochum report their findings in the journal Cells, published online on 28 May 2022.

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