Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent chronic liver disorders worldwide and can sometimes lead to severe conditions like cirrhosis and hepatocellular carcinoma. As such, early assessment of the severity of NAFLD is essential for timely intervention. Non-alcoholic steatohepatitis (NASH) and liver fibrosis are two important factors that determine NAFLD progression and probability of cirrhosis development, respectively. So far, liver biopsy has been the most widely recognized method for diagnosing and evaluating NASH and fibrosis. However, it is an invasive procedure that is susceptible to observer bias and suboptimal standardization.