Biological pathways found that drive genomic changes and bone metastasis in ewing sarcoma, a rare childhood cancer
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28 April 2022Biological pathways found that drive genomic changes and bone metastasis in ewing sarcoma, a rare childhood cancer
In studies using mice grafted with human Ewing sarcoma tissue, researchers from Georgetown University Medical Center and colleagues have identified a biological pathway that is activated when tissue is starved of oxygen due to rapid growth of a tumor, thereby allowing cancer cells to make genetic changes so they can metastasize to the bone and thrive even when exposed to chemotherapy.
