An international team of multiple sclerosis (MS) experts reported lack of association between cognition and physical activity and cardiorespiratory fitness in a large sample of individuals with progressive MS. These findings have important implications for studies involving exercise interventions aimed at treating the cognitive effects of MS. The article, titled “Cardiorespiratory fitness and free-living physical activity are not associated with cognition in persons with progressive multiple sclerosis: Baseline analyses from the CogEx study,” was published in Multiple Sclerosis Journal on October 1, 2021.