A review co-authored by Dr. Bradley Spieler, Vice-Chair of Scholarly Activity and Research in the Department of Radiology at LSU Health New Orleans School of Medicine, and Dr. Neil Baum, of Tulane’s Department of Urology, reports that although burnout affects more than 50% of health care workers, diagnostic radiologists are at even higher risk. Seventy-one percent of respondents to a 2019 survey of radiology practice leaders reported stress from workplace factors. The paper discusses causes and biological effects, risk factors, recognition, solutions, and a collective response to burnout. The paper is published online in Current Problems in Diagnostic Radiology.