Corpora amylacea (CA) are complex aggregates described in different organs and tissues associated with aging and degenerative processes. Described for the first time in 1779 by Giovanni Battista Morgagni in the prostate and in 1837 by Jan Evangelista Purkinje in the brain, these were named corpora amylacea (in Latin, starch bodies) by Rudolf Vichow in 1854 for their similiarities with this polysaccharide. However, more than two centuries after its discovery, its function and meaning are unknown yet.