Distress signal from fat cells prompts heart to shore up defenses against consequences of obesity
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20 August 2021Distress signal from fat cells prompts heart to shore up defenses against consequences of obesity
A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests. The finding, published online in Cell Metabolism, could help explain the “obesity paradox,” a phenomenon in which obese individuals have better short- and medium-term cardiovascular disease prognoses compared with those who are lean, but with ultimately worse long-term outcomes.
