New strategy for precise isolation and molecular analysis of circulating tumor cells and fusion cells
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4 August 2021New strategy for precise isolation and molecular analysis of circulating tumor cells and fusion cells
A century ago, German pathologist Otto Aichel discovered that tumor cells could fuse with immune cells, forming fusion cells with both immune cell motility and tumorigenic ability of tumor cells, which are more likely to spread and metastasize through the circulatory system. Due to the limitation of currently available approaches, such fusion cells are difficult to be isolated and analyzed thoroughly.
