Vivid photos of the red “COVID arm” rash and reports of facial swelling in patients who have received dermatological fillers after Pfizer-BioNTech or Moderna vaccination for COVID-19 may increase patients’ concerns about mRNA vaccine side effects and contribute to vaccine hesitancy. A comprehensive review in Clinics in Dermatology, conducted by University of Connecticut School of Medicine researchers and published by Elsevier, confirms that almost all cutaneous reactions are largely self-limited and should not discourage getting the vaccine.