New study results indicate that different comorbid conditions affecting individuals diagnosed with COVID-19 may impact how long they continue to receive positive SARS-CoV-2 polymerase chain reaction (PCR) test results. Individuals diagnosed with COVID-19 who are aged 60+, have three or more chronic medical conditions, particularly diabetes, obesity, rheumatologic disease, or an organ transplant, have positive PCR tests for longer periods of time compared to younger individuals without these comorbidities. However, the data showed no significant difference in the duration of positive PCR tests results by the degree of immunocompromise or for individuals receiving chemotherapy or steroids to treat COVID-19.