At the University of Kentucky Children and Young Adult Headache Program, recently there has been a surge in cases of new daily persistent headaches (NDPH). A few of these patients had tested positive for COVID-19 prior to persistent headaches and the majority of them remembered some mild viral illness prior to the persistent headache. It is not clear if these recent cases are directly linked to COVID-19 but there is a possibility. Although these headaches cause significant suffering by affecting the quality of life (calculated by PedMIDAS Score), there is no evidence that they may result in permanent damage.