Metabolic inhibitor IACS-6274 shows early antitumor effects in underserved patients
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20 May 2021Metabolic inhibitor IACS-6274 shows early antitumor effects in underserved patients
The glutaminase (GLS1) inhibitor IACS-6274, discovered and developed by The University of Texas MD Anderson Cancer Center’s Therapeutics Discovery division, appears to be well-tolerated with successful target inhibition and early signs of anti-tumor activity in a biomarker-driven Phase I trial. Interim results of the study will be presented at the 2021 American Society for Clinical Oncology (ASCO) Annual Meeting on June 4.
