PLD3 gene contributes to risk of Alzheimer’s disease
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8 April 2021PLD3 gene contributes to risk of Alzheimer’s disease
A rare and controversial mutation in the phospholipase D3 (PLD3) protein—previously linked to Alzheimer’s disease—interferes with PLD3’s vital recycling function inside neurons. Matthew Schrag of Vanderbilt University Medical Center and colleagues report these new findings in a paper published April 8th in PLOS Genetics.
