Direct reprogramming of oral epithelial cells into mesenchymal-like cells

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Direct reprogramming of oral epithelial cells into mesenchymal-like cells

Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with epigenetic agents. Subsequently, the progenitor stem-like cells were directly differentiated into endothelial, mesenchymal stem, and osteogenic cells that constitute the periodontal ligament.

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