Premature birth disrupts Purkinje cell function, resulting in locomotor learning deficits

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Premature birth disrupts Purkinje cell function, resulting in locomotor learning deficits

In the United States, one in 10 babies are born too soon, resulting in complications that can affect their locomotor development and influence such simple tasks as balance, walking and standing later in life. A new peer-reviewed study by Children’s National Hospital, published in the Proceedings of the National Academy of Sciences (PNAS), explores exactly what neural circuitry of the cerebellum is affected due to complications that occur around the time of birth causing these learning deficits, and finds a specific type of neurons—Purkinje cells—to play a central role.

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