The fact that cells are motile and come into contact with each other is one of biology’s fundamental principles. During embryonic development, cells must communicate with their neighbors in order to find their proper place in the differentiating organism. Wound healing is another process in which direct intercellular interactions are essential. In this context, motility enables cells to migrate to the location of the lesion and regenerate lost structures. Cancer cells also make use of this property to leave their site of origin in the primary tumor, which allows them to initiate the formation of metastatic tumors in other tissues.