ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver
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22 January 2021ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver
Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control. This toxicity has been regarded as a ‘black box’ and is mainly managed by an empirical approach, but there is no clear understanding of the mechanism. Now, researchers from Japan have found that a bit of attention to the types and frequencies of NSAIDs could help people avoid liver injury.
