As colleges and universities consider strategies for the spring semester to keep COVID-19 cases down, a study conducted by experts in epidemic modeling may help shed light on what mitigation strategies may be most effective, both in terms of infections prevented and cost. Investigators from Brigham and Women’s Hospital, Massachusetts General Hospital and Case Western Reserve University used the Clinical and Economic Analysis of COVID-19 interventions (CEACOV) model to perform their study, finding that combining a mandatory mask-wearing policy with extensive social distancing would prevent 87 percent of infections among students and faculty. Routine testing was also highly effective at preventing infections, but may be cost prohibitive for many colleges and universities. The team also reports that, even if campuses remain closed, there would likely be infections among faculty acquired from the surrounding community, as well as infections among students who return to live off campus in and around college towns. Results are published in Annals of Internal Medicine.